Cast: Eric McCormack, Deborah Messing, Sean Hayes, Megan Mullally, Shelley Morrisson, Harry Connick Jr., Michael Angarano, Sidney Pollack, Blythe Danner, Bobby Cannavale, Leslie Jordan, Eileen Brennan
- Air Dates: September 1998 - May 2006
Will is a successful Manhattan lawyer -- likable, handsome and charming - recently ended a long-term relationship. Likewise, Grace is a beautiful, self-employed interior decorator. They both love fine wine, fashion and shopping. Will and Grace have been friends for a long time, and though they're both looking for love, they long ago accepted the fact that there will be no romance between them - you see Will is gay. As a result, they face life's ups and downs together, knowing they will always have each other to lean on.
Grace's work life is complicated by her assistant, Karen Walker (Mullally), a wealthy socialite who only bothers to show up at work because it keeps her "down to earth" -- and because she likes to tell Grace how to live her life. Will has another good friend in the outrageous Jack McFarland (Hayes), a well-meaning but self-involved young man who comes with a complete matching set of emotional baggage.