Cameron Diaz will star in the Nick Cassavetes-directed "My Sister's Keeper" for New Line Cinema says Variety.

Jeremy Leven penned the adaptation of the Jodi Picoult novel, which follows a former defense attorney who returns to the courtroom to defend herself and her husband when they are sued by their 13-year-old daughter for emancipation.

The girl was conceived as a genetic match with the hope she could prolong her cancer-ridden sister's life. Shooting will begin early next year once Diaz wraps work on "The Box."