Saffron Burrows, Jada Pinkett Smith and Liv Tyler are in final negotiations to join the cast of the Mike Binder-directed drama "Reign O'er Me" for Columbia Pictures says The Hollywood Reporter.

Adam Sandler and Don Cheadle headline the film which centers on a man (Sandler) who lost his family in the Sept. 11 attacks and has not recovered from his grief. He runs into his college roommate (Cheadle), who is now a psychiatrist and is determined to help him cope with the loss.

Burrows would play Donna, a patient of Cheadle's character who has entanglements with both men. Smith is set to play Janeane, the wife of Cheadle's character, while Tyler would play Angela, a psychiatrist.