- Cast: Ben Stiller, Amy Adams, Robin Williams, Owen Wilson, Bill Hader, Jonah Hill, Ricky Gervais, Hank Azaria, Steve Coogan, Dick Van Dyke, Christopher Guest, Eugene Levy, Clint Howard, Thomas Lennon, Ed Helms, Mizuo Peck, Jake Cherry, Rami Malek, Robert Ben Garant, Patrick Gallagher, Jon Bernthal, Alain Chabat, Nick Dash, Regina Taufen
- Director: Shawn Levy
- Writers: Robert Ben Garant, Thomas Lennon, Scott Frank
- Producers: Michael Barnathan, Chris Columbus, Shawn Levy, Mark Radcliffe
- Executive Producers: Thomas M. Hammel, Josh McLaglen
- Art Directions: Michael Diner, Anthony Dunne, Helen Jarvis, Grant Van Der Slagt
- Castings: Heike Brandstatter, Coreen Mayrs
- D.O.P.: John Schwartzman
- Editors: Dean Zimmerman, Don Zimmerman
- Makeup: Emanuela Daus
- Music: Alan Silvestri
- Production Design: Claude Paré
- Set Decoration: Lin MacDonald
In the sequel, the Museum of Natural History is closed down for upgrading and the exhibits are put into storage at the Federal Archives in Washington, D.C. Amy Adams will play an undetermined historical figure who has a crush on security guard Larry (Stiller).
It's a new "Night" and "Museum" for Ben Stiller, who is joined by several other stars from the original film, as well as new characters from history -- including Amy Adams as famed aviatrix Amelia Earhart, Hank Azaria as villainous Egyptian pharaoh Kahmunrah, Christopher Guest as Russian tyrant Ivan the Terrible and Alain Chabat as Napoleon. Owen Wilson is back as cowboy Jedediah, and Robin Williams again rides into history as Teddy Roosevelt.
The centerpiece of the film will be bringing to life the Smithsonian Institution, which houses the world's largest museum complex with more than 136 million items in its collections, ranging from the plane Amelia Earhart flew on her nonstop solo flight across the Atlantic and Al Capone's rap sheet and mug shot to Dorothy's ruby red slippers and Archie Bunker's lounge chair. No major film has ever shot inside the Smithsonian in Washington...until "Night at the Museum: Battle of the Smithsonian."
- Aspect Ratio: 2.35:1
- Filming Locations: Los Angeles, USA; New York City, USA; Washington DC, USA
- MPAA Warning: Mild action and brief language
- Production Budget: $150 million
- Production Companies: 1492 Pictures, 20th Century Fox Film Corporation, Museum Canada Productions, Twentieth Century-Fox Film Corporation
- Production Schedule: 8 April 2008 - July 2008
- The first major Hollywood feature to be filmed at the Smithsonian in Washington, D.C.